Taking a Step Back from Back-Translocation: an Integrative View of LepA/EF4's Cellular Function

Taking a Step Back from Back-Translocation: an Integrative View of LepA/EF4's Cellular Function.

Protein synthesis, the translation of mRNA into a polypeptide facilitated by the ribosome, is assisted by a variety of protein factors, some of which are GTPases. In addition to four highly conserved and well-understood GTPases with known function, there are also a number of noncanonical GTPases that are implicated in translation but whose functions are not fully understood. LepA/EF4 is one of ...

Taking Computing Back to School

In this paper, we discuss the use of a kind of videoconferencing technology generally referred to as an “Access Grid” to connect universities with local schools and colleges. We report on successful trials of the Open Source form of this videoconferencing technology that are part of the “Taking Computing back to school” project due to be completed in July. The project is part-sponsored by both ...

Taking a Back Door to Target Myc

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One step forwards, one step back.

Cells step back in time

Models based on the crystal structure of interleukin-1 vary significantly. D eP ri st o/ El se vi er UK) warns that, for any given structure in the Protein Data Bank (PDB), there will be many other overlooked structures that are equally consistent with the data. Crystallized proteins retain the ability to move around, thus making interpretations of diffraction data an imprecise process. Crystal...